CBME was established in 1971 as a Joint venture of Indian Institute of Technology Delhi and All India Institute of Medical Sciences, Delhi. The Centre has applied engineering principles to address medical and biological problems. CBME has provided interdisciplinary insights to biological research for the development of health care technologies. Over the last two decades, the focus has shifted to include biological medicine, the behavior of molecular health systems for better and innovative drug delivery, development of biomaterials, rehabilitation engineering, development of medical devices and implants.